一、 教学成果(教学获奖、教学科研项目、大创指导获奖) 无 二、 科研成果(限填写第一作者或通讯作者的科研论文、科研获奖、著作、课题、科研转化) 代表性科研论文: (1)Jing Gao, Xunyun Liu, Min Wang, et al. Adenosine protects cardiomyocytes against acrolein-induced cardiotoxicity by enhancing mitochondrial homeostasis, antioxidant defense, and autophagic flux via ERK-activated FoxO1 upregulation. Ecotoxicol Environ Saf, 2024, 283: 116799. (2)Qingqing Ma, Jing Gao, Qiang Fan, et al. Thinned young apple polyphenols may prevent neuronal apoptosis by up-regulating 5-hydroxymethylcytosine in the cerebral cortex of high-fat diet-induced diabetic mice. Food Func, 2023, 14(7): 3279-3289. (3) Xuyun Liu, Jing Gao, Yizhen Yan, et al. Mitochondria-targeted triphenylphosphonium-hydroxytyrosol prevents lipotoxicity-induced endothelial injury by enhancing mitochondrial function and redox balance via promoting FoxO1 and Nrf2 nuclear translocation and suppressing inflammation via inhibiting p38/NF-кB pathway. Antioxidants, 2023, 12(1):175. (4)Jing Gao, Zhen Wang, Peipei Gao#, et al. Daphnetin alleviates senile and disuse osteoporosis by distinct modulations of bone formation and resorption. Antioxidants, 2022, 11:2365. (5)Jing Gao, Zhihui Feng, Xueqiang Wang, et al. SIRT3/SOD2 maintains osteoblast differentiation and bone formation by regulating mitochondrial stress. Cell Death & Differentiation, 2018, 25(2): 229-240. 主持科研项目: (1)2024.1-2026.12 国家自然科学基金委员会,青年项目,32300963,APOA4-NR1D1-SIRT3轴通过调控成骨细胞线粒体稳态改善骨丢失及运动干预的作用。 (2)2020.1-2021.12 陕西省科学技术厅,陕西省自然科学基础研究一般项目(青年),2020JQ-028,羟基酪醇靶向骨钙素调控成骨分化的分子机制研究。 (4)2018.3-2019.12 中国博士后科学基金会,面上项目,2018M633491,白藜芦醇靶向SIRT3促进成骨分化的分子机制探究。 |